An I2 value represents the percentage of total variation across studies due to heterogeneity rather than due to chance.15 Values of 25% https://www.jewelleryn394a.top, 50%, and 75% have been regarded as representing low, moderate, and high heterogeneity.15Sensitivity analyses were planned a priori using a few chosen groups to examine the effects of level of material wellbeing (developed v developing countries16), study quality (see web extra appendix 2), youth (adolescence v adulthood), and race. Three post hoc sensitivity analyses were carried out (see web extra appendix 3) to examine the effects of self reported compared with measured body mass index; body mass index assessed before pregnancy, during pregnancy, or post partum; and using exact cut offs for body mass index with a reference body mass index of 20 25 versus those with cut offs close to this.Quality assessmentTwo reviewers (two of ZH, SDM, and SM) independently assessed study quality using a predefined evaluation of six types of biases: selection, exposure, outcome, confounding, analytical, and attrition (see web extra appendix 2). This bias assessment tool has been described in other reviews undertaken by our group on determinants of preterm birth and low birth weight.17To deal with publication bias we showed results without imputation as well as with imputation: the latter using Duval and Tweedie’s trim and fill method for estimating and adjusting for the number and outcomes of missing studies in a meta analysis18 19 that is, to adjust for any observed publication bias.
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