Let’s look at the basis for Wyeth’s claim, which is the now famous study published in the British Journal of Psychiatry in 2001 by Thase et al (1) showing that Effexor’s remission rates were 45% (vs. 35% for SSRIs and 25% for placebo). The study had excellent methodology, comprising a pooled analysis of all the data the company had collected comparing Effexor with Prozac, Paxil, and Luvox.
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